United travel to Wolves bidding to follow up their comprehensive opening day win over Chelsea and keep pace with the early leaders.
Wan-Bissaka, who joined from Crystal Palace for £50million in the summer, is braced for loud backing from a vocal travelling support at Molineux.
“The crowd was amazing during the Chelsea game and I’ve heard great things about United’s away following as well,” Wan-Bissaka said.
“Now it’s up to us to give them something to celebrate at Wolves.”
Wan-Bissaka travelled with his new team-mates during their pre-season tour of Australia, China and Singapore following his move from south London in June.
The 21-year-old, who rose through the academy at Palace, says he is now settled in his new surroundings and “feels a part of things” at Old Trafford two months after his big move.
“I’ve become quite close to Axel Tuanzebe since joining the club,” added Wan-Bissaka.
“He’s taken me under his wing a bit, though I must admit the whole squad has been looking after me.
“It has been really easy to come here and feel a part of things. Nobody’s left me out of anything; they all speak with me and interact and that’s really good. It’s been a huge help and I’d like to thank the fans, too, for giving us such support.”